Unable to open an office file on Sharepoint server post M365App migration
Below is a small kb which allows you to resolve problems related to opening a file on a SharePoint OnPrem server from a client having migrated from Office 2016 to the M365Apps solution. Correction To correct the issue, you must clear office cache and Rename a registry key . Clear Office cache : Close all Office 2016 app Navigate to C:\Users username\AppData\Local\Microsoft\Office\16.0 Rename the folder 16.0 to 16.0_old Rename the Registry Key Open "Regedit" Navigate to Computer \ HKEY_CURRENT_USER\ Software \ Microsoft \ Office \ 16.0 \ Common \ ServicesManagerCache Rename ServicesManagerCache to ServicesManagerCache_old After applying all of these changes, you can again open your files hosted on your SharePoint server.